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An Introduction to Molecular Medicine and Gene Therapy
by (Editor: Thomas F. Kresina)
Product Group: Book
Publisher: Wiley-Liss (2000-10-27)
ISBN: 0471391883
EAN: 9780471391883
Dewey Decimal #: 616.042
Binding/Media: Hardcover - 386 pages
Edition: 1
SKU: 60742
Condition: Used: Good
Comments: Ex-library book with usual stickers and markings. Typical library reading and shelf wear. Has a SALVAGE stamp inside or on page edges.
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Editorial Reviews
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Product Description
An Introduction to Molecular Medicine and Gene Therapy
Edited by Thomas F. Kresina, Ph.D. Gene therapy, or the use of genetic manipulation for disease treatment, is derived from advances in genetics, molecular biology, clinical medicine, and human genomics. Molecular medicine, the application of molecular biological techniques to disease treatment and diagnosis, is derived from the development of human organ transplantation, pharmacotherapy, and elucidation of the human genome. An Introduction to Molecular Medicine and Gene Therapy provides a basis for interpreting new clinical and basic research findings in the areas of cloning, gene transfer, and targeting; the applications of genetic medicine to clinical conditions; ethics and governmental regulations; and the burgeoning fields of genomics, biotechnology, and bioinformatics. By dividing the material into three sections - an introduction to basic science, a review of clinical applications, and a discussion of the evolving issues related to gene therapy and molecular medicine-this comprehensive manual describes the basic approaches to the broad range of actual and potential genetic-based therapies. In addition, An Introduction to Molecular Medicine and Gene Therapy:
* Covers new frontiers in gene therapy, animal models, vectors, gene targeting, and ethical/legal considerations
* Provides organ-based reviews of current studies in gene therapy for monogenetic, multifactoral or polygenic disorders, and infectious diseases
* Includes bold-faced terms, key concepts, summaries, and lists of helpful references by subject in each chapter
* Contains appendices on commercial implications and a review of the history of gene therapy
This textbook offers a clear, concise writing style, drawing upon the expertise of the authors, all renowned researchers in their respective specialties of molecular medicine. Researchers in genetics and molecular medicine will all find An Introduction to Molecular Medicine and Gene Therapy to be an essential guide to the rapidly evolving field of gene therapy and its applications in molecular medicine.
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Customer Reviews
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Excellent overview of a fascinating field
Rating  (4)
Date: 2001-12-02
I did not have any special prior knowledge in biology or genetics. I needed to quickly get up to speed in this area for a professional reason. Parts of the book were a little difficult to understand at times, especially when it used many technical terms, but overall it provided me with an excellent overview of this fascinating and rapidly evolving field. I reduced one star because of not seeing enough illustrations and diagrams which in my view are essential in any text that includes complex concepts. With this book I also read "Genomes" to complement the basics of Genomics and together these two books did the trick!! Strongly reccomended to anyone who is interested in the field.
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Rating  (5)
Date: 2000-12-14
2 out of 2 customers found this reveiw helpful
The greatest difficulty with this field is that it is currently evolving at a rapid rate. Thus, books on the subject run the risk of being outdated before publication. However, Kresina and co-authors have done a solid job of reviewing existing methodologies, ethics and regulation of gene therapy as well as identifying some of the diseases for which this novel type of therapy could be applied. --Grant MacGregor, Emory University
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An outstanding introduction
Rating (5)
Date: 2000-12-14
2 out of 2 customers found this reveiw helpful
I am very impressed with the breadth of subjects that Dr. Kresina covered and how he was able to relate their associations with either molecular medicine and/or gene therapy. More importantly, he draws the two disciplines together in a logical and constructive manner. The book is not only an outstanding introduction to molecular medicine and gene therapy, but will be a valued reference guide for much of the information contained in the chapters. The topics are timely and most of the authors extremely well known and respected in their respective fields. While the second section of the book is primarily the clinical application, it draws very nicely from the more basic science introductory chapters. Chapters 13-15 and the Appendix provide a discussion of issues which undoubtedly will become significantly associated with advances in molecular medicine and gene therapy. The book is laid out in an easy-to-read format and provides ready access to a variety of different subjects. The index is inclusive and the chapters cover their individual areas in an up-to-date manner..."An Introduction..." should remain an outstanding introduction and reference text for a variety of students - from undergraduate to postdoctoral to all levels of faculty and investigators. --Clifford J. Steer, M.D., University of Minnesota Medical School
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